Evidence-Based Interventions for Autism: Clinical Trials

EBIA-CT Database

A comprehensive scientific platform synthesizing evidence from over 400 clinical trials (25,000+ participants) to support informed decision-making about autism interventions across the lifespan.

28
Intervention types
97
Meta-analytic reports
368
Unique meta-analyses
400+
Clinical trials
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For clinicians

Making informed shared-decision making in clinical practice possible

EBIA-CT bridges the gap between scientific results and clinical practice, by making complex evidence accessible to all stakeholders involved in autism care.

Shared decision making

Facilitates collaborative discussions between healthcare professionals, individuals with autism, and their families by providing clear, accessible evidence about intervention efficacy and safety.

Comprehensive evidence

Constitutes the largest database of scientific data on complementary/alternative and psychosocial interventions in autism (pharmacological interventions coming during summer 2025), providing the most complete picture of available treatment options.

Transparent methodology

Employs a rigorous methodology, with all data on the website validated through publication in high-impact scientific medical journals, ensuring reliable and unbiased information for informed decision-making

Watch our platform overview to learn how to navigate EBIA-CT

For researchers

How EBIA-CT was created

The largest scientific evidence synthesis of the interventions effects for autism to date.

Comprehensive literature search

Systematic searches across 5 major scientific databases identified over 7,000 potentially relevant publications, ensuring no significant evidence was overlooked in our synthesis.

Rigorous selection

Trained reviewers evaluated the methodological quality of each meta-analysis using a validated tool: each result presented in the intervention/preference sections is coming from the highest-quality scientific paper available to date (even if some areas were still covered only by low-quality papers).

Advanced statistical re-analysis

All meta-analyses were re-computed using consistent statistical methods, providing standardized effect sizes and objective confidence ratings across all interventions.

Interactive platform development

Results were transformed into an accessible, user-friendly platform with input from clinicians, researchers, and autism community members to ensure practical utility.

Published in leading scientific journals

The methodology and findings have been peer-reviewed and published in several of the field's most prestigious journals:

Nature Human Behaviour
2025
Molecular Psychiatry
2022

Project Leaders

Corentin J. Gosling, PhD
Université Paris Nanterre
Université Paris Cité
University of Southampton
Corentin Gosling is an Associate Professor of Neuropsychology at Université Paris Nanterre. He is also a visiting researcher at University of Southampton. His research interests focus on the dissemination of knowledge about interventions for mental disorders and developping new methodological and statistical tools for evidence synthesis.
Ariane Cartigny, MSc
Université Paris Cité, FR
Hôpital Robert Debré, FR
 
Ms. Ariane Cartigny is a clinical neuropsychologist. She currently works at the Excellence Centre for Autism and Neurodevelopmental Disorders at Robert Debre Hospital. Since 2020, she co-leads the team of neuropsychologists of the FondaMental network in France.
Richard Delorme, MD, PhD
Robert Debré Hospital, FR
Institut Pasteur, FR
 
Dr. Richard Delorme is the Head of the Center of Excellence for Autism and Neurodevelopmental Disorders at Robert Debré Hospital in Paris, France. He has participated in the identification of the first genes involved in autism. He is the senior author of this project.

Core Members of the Team

Samuele Cortese, MD, PhD
University of Southampton
Solent NHS Trust
New York University
Samuele Cortese is currently Professor of Child and Adolescent Psychiatry at the University of Southampton and Honorary Consultant Child and Adolescent Psychiatry for Solent NHS Trust. He ranks #1 worldwide in terms of expertise on ADHD and #2 in child psychiatry according to Expertscape. He is also listed among the top 0.1% most cited researchers in the field of Psychology and Psychiatry.
Marco Solmi, MD, PhD
University of Ottawa
Charité University Medicine
 
Marco Solmi is Associate Professor of Psychiatry at University of Ottawa. His clinical focus is on prevention/early intervention for mental disorders, physical health in mental disorders, and psychopharmacology. He ranks #5 worldwide in terms of expertise in systematic reviews and meta-analysis according to Expertscape. He is also listed among the top 0.1% most cited researchers in the field of Psychology and Psychiatry.
Paolo Fusar-Poli, MD, PhD
King's College London, UK
South London and Maudsley NHS
Foundation Trust, UK
Dr. Paolo Fusar-Poli is a Professor of Preventive Psychiatry at King's College London where he heads the EPIC Lab. He ranked as the number two expert in psychosis in the world in 2019 according to expertscape and he was an external advisory member for the DSM-5 and DSM-5TR Psychosis Working Group, US
Joaquim Radua, MD, PhD
Hospital Clinic de Barcelona, Spain
King's College London, UK
Karolinska Institutet, Sweden
Dr. Joaquim Radua is a psychiatrist medical doctor and statistician interested in improving the treatment of psychiatric disorders. He is the developer of numerous methods for meta-analysis of neuroimaging studies and he has been named as one of the most cited researchers in Psychiatry and Psychology..
Micheal P Sandbank, PhD
University of North Carolina
at Chapel Hill, US
 
Dr. Micheal Sandbank is an internationally-recognized expert on early interventions for young children on the autism spectrum. She is the lead researcher on Project AIM, a scoping systematic review and meta-analysis of all group design studies of interventions for young children on the autism spectrum.
Klara Kovarski, PhD
Université Paris Cité
 
 
Klara Kovarski is a lecturer at Sorbonne University (INSPE-Paris). After graduating in philosophy from the University of Genoa, she obtained a master's degree in cognitive science (Cogmaster) and in philosophy of science (Lophisc) in 2013. She completed a PhD in cognitive neuroscience at the University of Tours under the supervision of Magali Batty (Inserm, iBrain, 2018), and a PhD mobility in Margot Taylor's laboratory (Sickkids Hospital, Toronto).
Serge Caparos, PhD
Université Paris 8, FR
Institut Universitaire de France, FR
 
Dr. Serge Caparos is an associate professor of cognitive psychology at Paris VIII University. His research interests focus on the links between emotion and cognition, with neurodevelopmental and crosscultural perspectives.